Science of



Science of


What is the impact of migraine beyond the headache?

Beyond the headache, there are a number of non-headache symptoms that may have a significant impact on the lives of patients with migraine.1-5

Explore this website to understand the current findings on the pathophysiology underlying this disease and how this may impact the clinical management of your patients with migraine.6


Watch this brief video highlighting migraine-associated patient burden and new insights into migraine pathophysiology.

Reproduced from Edvinsson L, et al. Eur J Neurol. 1998;5:329-341, by permission of John Wiley & Sons, Inc.

  • Migraine overview
    and impact

    Read on for current information about migraine and its disease burden.

  • CGRP and its

    Read current research on CGRP signaling in migraine.

  • Update on

    Andrew Charles MD discusses the biological pathways that underlie the symptoms associated with migraine.

  • Structural and functional
    impact on the brain

    Christoph Schankin MD discusses the potential implications of migraine for brain structure and function.

  • Resource library

    Explore additional
    resources of interest.